Vincristine Neuropathy

Although vincristine sulfate (Vincasar PFS®) can be an effective chemotherapy drug for treating acute leukemia in many adults and children, it may cause problems in some people.
For instance, there have been reports of vincristine causing nerve problems (neuropathy), which may get worse the longer you receive treatment. Make sure your healthcare provider knows if you have a condition affecting your nerves and muscles, as you may need to be monitored more closely or may need a lower vincristine dosage. Also, let your healthcare provider know immediately if you develop signs of nerve problems during treatment, such as:
  • Numbness, tingling, pricking, or burning sensations in your hands or feet
  • Joint or muscle pain
  • Pain in your face, jaw, or head
  • Dizziness or faintness, especially when rising from a seated or lying position.
(To learn more, click Precautions and Warnings With Vincristine. This resource discusses some of the complications that may occur with this chemotherapy drug and explains what to talk to your healthcare provider about before beginning treatment).
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