Tabloid Uses

The prescription drug Tabloid is used to treat a type of blood and bone marrow cancer called acute myeloid leukemia (AML). It works by disrupting how the cancer cells grow and divide. There are also some unapproved uses for this medicine, such as treating psoriasis, Crohn's disease, and ulcerative colitis.

What Is Tabloid Used For?

Tabloid® (thioguanine) is a prescription medication approved to treat acute nonlymphocytic leukemia, more commonly called acute myeloid leukemia or acute myelogenous leukemia (AML). It belongs to a group of medicines known as purine analogs. Tabloid is sometimes referred to as 6-thioguanine, or simply TG.
AML is a type of cancer that occurs when the body produces too many of a certain type of immature blood cell called myeloid cells. Myeloid cells normally develop into mature red blood cells, white blood cells, and platelets. However, when someone has AML, abnormal myeloid cells do not develop into healthy blood cells.
The abnormal cells associated with AML (called leukemia cells) grow rapidly, with no control, and eventually crowd out normal, healthy blood cells. As the number of platelets, red blood cells, and white blood cells decline, a person with AML becomes more susceptible to infection, anemia, or easy bleeding. The leukemia cells can also spread outside the blood to other parts of the body, including the central nervous system (brain and spinal cord), skin, and gums.
As its name indicates, AML is an acute leukemia, which means it progresses rapidly. In contrast, chronic forms of leukemia develop more slowly (see Types of Leukemia for more information about the different types of this disease). AML occurs in both adults and children.
There are several types of treatment available for AML, including chemotherapy, radiation therapy, and stem cell transplant. In general, treatment falls into two phases: remission induction therapy and consolidation therapy.
The goal of remission induction therapy is to kill the leukemia cells in the blood and bone marrow, and bring the disease into remission. Even after induction therapy, there are usually some leukemia cells that remain. Without further treatment, these cells could cause a relapse. The goal of consolidation therapy is to destroy the remaining leukemia cells, and prevent a relapse of the disease.
Tabloid is a type of chemotherapy approved for the induction and consolidation treatment of acute myelogenous leukemia. It is usually given in combination with other medicines, as remission is less likely and the duration of remission is usually shorter when Tabloid is used alone.
The response to Tabloid treatment can differ by age, and whether the AML has been treated previously. In general, younger people and those who were previously untreated do better on Tabloid.
Because the long-term use of Tabloid may cause liver damage, the drug is not recommended for maintenance treatment or any other long-term continuous treatment. Maintenance treatment is treatment that continues for several years to keep leukemia in remission.  
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Tabloid Medication Information

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