Tabloid and Pregnancy

Is it safe for pregnant women to use Tabloid (thioguanine)? Animal studies, as well as some reports of human use, suggest that this drug may cause miscarriage and birth defects. Because this medicine may harm an unborn child, it is generally recommended that women use an effective form of birth control during Tabloid treatment.

Can Pregnant Women Take Tabloid?

Tabloid® (thioguanine) is a prescription medication approved to treat a certain type of leukemia. This product is considered a pregnancy Category D medicine, which means it may cause harm to an unborn child if taken during pregnancy.
 

What Is Pregnancy Category D?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category D is a classification given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the risks the drug presents. A pregnancy Category D medicine may still be given to a pregnant woman if her healthcare provider believes that the benefits to the woman outweigh the possible risks to her unborn child.
 
When given to pregnant rats at five times the normally recommended equivalent human dose, Tabloid caused a variety of problems, including miscarriages, birth defects of the skull and bones, and incomplete development of the arms and legs. The drug has not been studied in pregnant women.
 
There are reports of women taking Tabloid during pregnancy. In these reports, the medication has been associated with miscarriages. In addition, an infant born to a woman treated with Tabloid during pregnancy was born with incomplete fingers and toes. It should be pointed out that it is not entirely clear whether the problems were due to Tabloid or something else. 
 
Because of the potential risks, Tabloid is generally not recommended for pregnant women. Women of childbearing potential should use an effective form of birth control to avoid becoming pregnant during treatment. Talk to your healthcare provider about the best birth control options for your particular situation.
 
Pregnancy and Pain

Tabloid Medication Information

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