Sprycel Uses

Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (sometimes called acute lymphocytic leukemia, or ALL) is a rapidly progressing leukemia in which the bone marrow produces a large number of lymphocytes (a type of white blood cell). The lymphocytes crowd out the healthy white blood cells, red blood cells, and platelets. As a result, infections, anemia, and bleeding may occur.
ALL is the most common type of leukemia in young children, but it can also affect adults. The Ph chromosome is also found in people with ALL.
Sprycel is approved for people with Ph chromosome-positive ALL that was resistant to other medications. It is also used for people who cannot tolerate other leukemia medications.

How Does It Work?

Protein kinases are proteins found in the body that regulate cell function, including cell growth. Sprycel works by reducing the activity of BCR-ABL tyrosine kinase, a type of protein kinase that causes the growth of leukemia cancer cells. By reducing BCR-ABL activity, Sprycel slows down the growth of leukemia cancer cells.

Is It Safe for Children to Use Sprycel?

This medication has not been adequately studied in children. It is only approved for use in people 18 years of age and older. Talk to your child's healthcare provider about the risks and benefits of using Sprycel in children.

Can Older Adults Use Sprycel?

Sprycel can be used in older adults. In clinical studies, older adults responded as well to the medication as younger age groups. However, older adults are more likely to experience Sprycel side effects and may need to be monitored more closely.

Off-Label Uses

On occasion, your healthcare provider may recommend this medicine for treating something other than the conditions discussed in this article. This is called an "off-label" use. Possible off-label uses for Sprycel include the treatment of the following conditions:
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Sprycel Medication Information

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