Sprycel Side Effects

Some of the most commonly reported side effects of Sprycel include fluid retention, diarrhea, and nausea. While reactions such as these are typically minor, there are some potentially serious complications that require immediate medical treatment. For example, contact your healthcare provider right away if you develop breathing problems, a severe headache, or any signs of an infection.

An Introduction to Sprycel Side Effects

Just like any medicine, Sprycel® (dasatinib) can cause side effects. Like other cancer medications, the side effects can be significant. Although not everyone who takes the medication will have problems, most people will experience some type of side effect during Sprycel treatment. Talk to your healthcare provider about ways to manage these side effects.
(This article covers many, but not all, of the possible side effects with this drug. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Sprycel

Sprycel has been studied extensively in clinical trials. In these studies, the side effects that occurred in people taking Sprycel were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most common Sprycel side effects included:
  • Fluid retention (edema) -- in up to 35 percent of people
  • Headaches -- up to 33 percent
  • Diarrhea -- up to 31 percent
  • Bleeding -- up to 26 percent
  • Fatigue -- up to 24 percent
  • Nausea -- up to 24 percent
  • Low blood cell counts -- up to 22 percent
  • Skin rash -- up to 21 percent
  • Shortness of breath -- up to 20 percent
  • Muscle pain -- up to 19 percent
  • Fever -- up to 18 percent.
Other common side effects, occurring in 1 to 16 percent of people, included:
  • Vomiting
  • Infections, including viral, bacterial, and fungal infections
  • Joint pain
  • Abdominal (stomach) pain or swelling
  • Mouth sores, inflammation, or pain (see Mouth and Gum Problems During Chemotherapy)
  • Heartburn or indigestion
  • Constipation
  • Tiredness or weakness
  • Chest pain
  • Chills
  • Itching
  • Hives
  • Hair loss
  • Skin problems, such as dry skin, itching, and eczema
  • Excessive sweating
  • Coughing
  • Tingling, pricking, or numbing sensations of the skin
  • Dizziness
  • Changes in taste
  • Drowsiness
  • Muscle weakness
  • Weight changes
  • Appetite loss
  • Increased heart rate
  • Vision problems, such as blurred vision
  • Increased blood pressure (hypertension)
  • A sudden redness and warmth of the face, neck, and chest (flushing)
  • Insomnia
  • Depression
  • Ringing in the ears.
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Sprycel Medication Information

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