Sprycel Drug Interactions

Taking denosumab with Sprycel could increase your risk for potentially serious infections. Talk to your healthcare provider before taking these medicines together. Also, contact your healthcare provider if you develop any symptoms of an infection, such as fever, chills, aches and pains, or coughing.
Sprycel may be less effective if it is taken with echinacea. Do not take these medications together unless your healthcare provider tells you otherwise.
Ergot Medications
Sprycel may increase blood levels of ergot medications, which could increase the risk for potentially serious side effects. Your healthcare provider may choose to monitor you more closely if you take Sprycel with an ergot medication.
Combining fentanyl with Sprycel may increase the amount of fentanyl in your bloodstream to potentially dangerous levels. Your healthcare provider may monitor you more closely for side effects if you take these medicines together.
H2 blockers
H2 blockers decrease the amount of Sprycel absorbed from the stomach into the body, potentially making Sprycel less effective. Do not take an H2 blocker during Sprycel treatment, unless your healthcare provider tells you otherwise.
Combining leflunomide and Sprycel may increase your risk for low blood cell counts, including abnormally low red blood cells, white blood cells, and platelets. This could increase your risk for severe anemia, infection, and bleeding. Your healthcare provider will monitor you for these problems if you take these medications together.
Live Vaccinations
Live vaccines are vaccines that contain live viruses or bacteria. If you receive a live vaccine while taking Sprycel, you might become infected with the virus or bacteria from the vaccine. Also, live vaccines may be less effective in people taking Sprycel. Talk to your healthcare provider before receiving a vaccination or immunization while taking this medication.
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Sprycel Medication Information

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