Rituxan Uses

How Does Rituxan Work?

Rituxan is an antibody that binds to a specific antigen (known as CD20 antigen) on the surface of B cells. B cells are a type of lymphocyte (white blood cell) that plays a role in the immune system and inflammation. By binding to the CD20 antigen, Rituxan signals the body to destroy the B cells (including cancerous B cells, if the medication is being used to treat cancer).
 
Interestingly, Rituxan is made by fusing part of a mouse antibody with part of a human antibody and is grown in the ovary cells of Chinese hamsters.
 

Can Children Use Rituxan?

Rituxan is approved only for use in people age 18 and older, as it has not been adequately studied in children. Talk with your child's healthcare provider about the benefits and risks of using Rituxan in this age group.
 

Off-Label Uses

On occasion, your healthcare provider may recommend this product for something other than the conditions listed in this article. These are known as off-label uses. Some of the possible off-label uses for Rituxan include treating the following conditions:
 
  • Hodgkin's lymphoma
  • Autoimmune hemolytic anemia in children
  • Chronic immune thrombocytopenic purpura (ITP)
  • Graft-versus-host disease.
     
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Rituxan Medication Information

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