Nipent Warnings and Precautions

Make sure to discuss your medical history with your healthcare provider before starting treatment with Nipent, as this chemotherapy drug may cause severe and sometimes life-threatening complications in people who have problems with their kidneys, liver, or lungs. Also, Nipent safety precautions include warnings for women who are pregnant or nursing and for people who are taking certain medications.

 

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to receiving Nipent® (pentostatin) if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Lung disease
  • Plans to receive a vaccination
  • An infection of any kind
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings for Nipent

Some warnings and precautions to be aware of prior to receiving this medication include the following:
 
  • Nipent can cause serious and potentially life-threatening side effects. It should only be given under the supervision of a healthcare provider with experience prescribing chemotherapy medicines.
 
  • This drug should only be used at the recommended doses. Higher amounts may increase the risk for severe lung, kidney, liver, and nervous system side effects.
 
  • Nipent may cause abnormally low blood cell counts, including low white blood cells, red blood cells, and platelets, which could increase your risk for life-threatening infections, anemia, and bleeding problems. Your healthcare provider will monitor your blood cell counts frequently, especially in the beginning of treatment when the risk appears to be highest.
     
Click the following articles to learn more about these potential side effects, as well as possible symptoms you should report immediately to your healthcare provider:
 
 
  • If you currently have an infection of any kind, your healthcare provider may choose to delay Nipent treatment until your infection is adequately under control. This drug could make your infection worse.
 
  • Nipent has been reported to increase liver enzymes, which could be a sign of liver problems. This side effect is generally reversible once treatment is stopped.
 
  • This medicine may cause kidney damage, especially when used in doses higher than the normally recommended amount. If kidney problems occur at recommended doses, they are usually minor and reversible.
 
  • There have been reports of severe rashes occurring in people treated with Nipent. Rashes associated with the drug may worsen if treatment continues. If you develop a rash, you may need to stop treatment until your rash improves.
 
  • This medication may cause nervous system toxicity (the nervous system includes the brain, nerves, and spinal cord). Your healthcare provider may recommend you stop Nipent treatment to prevent serious problems. Seek immediate medical attention if you experience signs of nervous system problems, such as:
    • Confusion
    • Numbness or tingling of the hands or feet
    • Problems with coordination
    • Weakness.
 
  • Your healthcare provider will order blood tests and other tests to monitor your response to this medication and monitor you for potentially serious side effects. Make sure to keep all of your laboratory and other healthcare appointments during treatment.
   
  • Nipent is a pregnancy Category D medication, which means it may harm an unborn child if used during pregnancy. Talk to your healthcare provider about the risks and benefits of using this medication when pregnant (see Nipent and Pregnancy).
 
  • It is unknown whether Nipent passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to receiving the drug (see Nipent and Breastfeeding).
 
5 Easy Tips to Manage Visitors During Cancer Treatment

Nipent Chemotherapy Information

Referring Pages:
Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.