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Nipent Drug Interactions
Talk to your healthcare provider before taking products like echinacea, FluMist, or certain other medications during treatment with Nipent. Combining these products can lead to dangerous drug interactions, which may cause serious side effects or a decreased effectiveness of the medications. In some cases, you may need to be monitored closely or avoid certain products.
Nipent® (pentostatin) may interact with a few other medications. Some of the drugs that may react with Nipent include but are not limited to:
- Amphotericin B (Abelcet®, AmBisome®, Amphotec®)
- Carmustine (BiCNU®)
- Certain immunosuppressant medications, such as:
- Denosumab (Prolia®)
- Leflunomide (Arava®)
- Natalizumab (Tysabri®)
- Pimecrolimus (Elidel®)
- Tacrolimus (Prograf®, Protopic®)
- Trastuzumab (Herceptin®)
- Clozapine (Clozaril®, FazaClo®)
- Cyclophosphamide (Cytoxan®)
- Echinacea
- Etoposide, etoposide phosphate (Etopophos®), and etoposide injection (Toposar®)
- Fludarabine (Fludara®)
- "Live" vaccinations, such as:
- Chickenpox vaccine (varicella vaccine)
- FluMist® (the nasal vaccine for influenza; the injected vaccine is not live)
- MMR vaccine (measles, mumps, rubella vaccine)
- Polio vaccine
- Rotavirus vaccine
- Smallpox vaccine
- Yellow fever vaccine
- BCG vaccine (used in some countries for tuberculosis)
- Nelarabine (Arranon®)
- Pegademase bovine (Adagen®)
- Roflumilast (Daliresp®)
- Sipuleucel-T (Provenge®).
Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD