Available by prescription only, Mustargen is used for treating certain types of cancer, including lung cancer, blood and bone marrow cancers, and others. This medicine is designed to help slow down the growth and multiplication of cancer cells. There are also some unapproved (off-label) uses for this drug, such as treating brain tumors, Langerhans cell histiocytosis, or actinic reticuloid.
What Is Mustargen Used For?Mustargen® (mechlorethamine) is a prescription chemotherapy medication. It belongs to a group of medicines called alkylating agents. There are several types of alkylating agents. Mustargen is a type of alkylating agent known as a nitrogen mustard.
Mustargen is approved to treat several types of cancer, primarily cancers of the blood and bone marrow. More specifically, the medication is approved to treat the following cancers:
- Hodgkin's disease (also known as Hodgkin's lymphoma)
- Lymphomas (Non-Hodgkin's lymphoma)
- Chronic myelocytic leukemia (also called chronic myelogenous leukemia)
- Chronic lymphocytic leukemia
- Polycythemia vera (a cancer of the bone marrow that leads to an abnormally high number of red blood cells)
- Mycosis fungoides (also called Sézary syndrome), a rare lymphoma that affects the skin
- Bronchogenic carcinoma (lung cancer).
Mustargen is also approved to treat metastatic cancer associated with effusion. Metastatic cancer is cancer that has spread from its original site to other areas of the body. Effusion occurs when excess fluid builds up in the space between membranes that line body organs, such as the lungs or abdomen (stomach).
In some cases, metastatic cancer may cause effusion, and cancer cells may be found in the excess fluid. When used to treat effusion from metastatic cancer, Mustargen is given directly into body cavities, such as the lining of the lungs, heart, or abdomen (stomach).
Mustargen is considered a palliative treatment. Palliative treatment is treatment that is aimed at reducing symptoms of a condition to make a person more comfortable, and improving quality of life. Palliative treatment does not cure a disease. Therefore, Mustargen is not expected to cure cancer.