Multiple Sclerosis and Mitoxantrone

Mitoxantrone (Novantrone®) is a medicine used for the treatment of several medical conditions. Specifically, it is prescribed to treat:
Mitoxantrone works by damaging DNA, preventing it from multiplying and dividing. When used for treating multiple sclerosis, mitoxantrone also works by preventing B-cells, T-cells, and macrophages from rapidly multiplying. These cells are thought to be involved in the immune response that causes the attack on myelin in people with MS. 
(Click What Is Mitoxantrone Used For? to learn more about using this drug to treat multiple sclerosis and certain types of cancer. This article also discusses in more detail how it works and whether there are off-label uses.)
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