Mitoxantrone Side Effects

Some of the possible side effects of mitoxantrone include fatigue, nausea, and upper respiratory tract infections. Studies have shown that most people who use this drug will develop some type of reaction. Because mitoxantrone is associated with potentially serious problems, such as dangerous infections and heart problems, let your healthcare provider know immediately if you develop anything that doesn't seem right.


An Introduction to Side Effects of Mitoxantrone

Just like any medicine, mitoxantrone (Novantrone®) can cause side effects. And, like most cancer medicines, the side effects can be significant. Although not everyone who uses the medication will have problems, most people will experience some type of mitoxantrone side effect. If adverse reactions do occur, in many cases they are minor and are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with mitoxantrone. Your healthcare provider can discuss a more complete list with you.)

Serious Mitoxantrone Side Effects

Some side effects of mitoxantrone should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an infection, such as:
    • Fever
    • Aches and pains
    • Chills
    • A sore throat
    • Cough
    • Painful urination
  • Signs of anemia, such as:
    • Fatigue
    • Pale skin
    • Shortness of breath
  • Any unusual bleeding or bruising
  • Black, tarry, or bloody stools
  • Signs of heart problems, such as:
    • Sudden weight gain
    • Swelling of the legs, ankles, or feet
    • Shortness of breath
    • A rapid or pounding heartbeat
  • Reactions at the site of your injection, such as:
    • Redness
    • Pain
    • Swelling
    • Burning
    • A bluish color of the skin
  • Severe or persistent swelling, sores, or pain in the lining of the mouth or throat
  • Yellowing of the skin or whites of the eyes (jaundice)
  • Severe or persistent nausea, vomiting, or diarrhea
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing.
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Mitoxantrone Drug Information

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