Mitoxantrone Dosage

The amount of mitoxantrone your healthcare provider prescribes will largely be based on your body surface area, which is calculated using your height and weight. This medicine is given as an injection into a vein. How often you receive it will depend on the condition being treated. Your healthcare provider will administer each mitoxantrone dose in a healthcare setting.

 

An Introduction to Your Dosage of Mitoxantrone

The dose of mitoxantrone (Novantrone®) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your height and weight
  • The reason you are using it
  • How you respond to and tolerate it.
 
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

Recommended Mitoxantrone Dosing Guidelines for Multiple Sclerosis

The usual recommended mitoxantrone dosage for treating multiple sclerosis is based on body surface area, which is usually calculated using your height and weight. More specifically, the recommended dose is 12 mg per m3, given once every three months.
 
Your healthcare provider will do certain tests before each dose to check your heart, liver, and blood cell counts. If you are a woman of childbearing potential, you will also need to have a pregnancy test before receiving each mitoxantrone dose.
 
You should receive no more than a total of 140 mg per m3 of this medicine during your entire lifetime. Higher total lifetime doses increase the risk for heart failure.
 

Mitoxantrone Dose for Hormone-Refractory Prostate Cancer

The usual recommended mitoxantrone dosage for treating people with hormone-refractory prostate cancer is based on body surface area, which is usually calculated using your height and weight. More specifically, the recommended amount is 12 to 14 mg per m3, given every 21 days (every three weeks). 
 
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Mitoxantrone Drug Information

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