Leukemia Channel
Topics
Medications
Quicklinks
Related Channels
Drug Interactions With Mitoxantrone
Certain medications, such as clozapine, leflunomide, and tofacitinib, can cause problems when they are used in combination with mitoxantrone. Drug interactions can also occur when this medicine is used with herbal supplements like echinacea or even live vaccinations. Some of these combinations can increase your risk for serious side effects or decrease the effectiveness of the products.
from eMedTV.comMitoxantrone (Novantrone®) can potentially react with several other medications. Some of the medicines that may lead to drug interactions with mitoxantrone include but are not limited to:
- Amphotericin B (Abelcet®, AmBisome®, Amphotec®)
- Clozapine (Clozaril®, FazaClo®)
- Denosumab (Prolia®)
- Echinacea
- Leflunomide (Arava®)
- "Live" vaccinations, such as:
- Chickenpox vaccine (varicella vaccine)
- FluMist® (the nasal vaccine for influenza; the injected vaccine is not live)
- MMR vaccine (measles, mumps, rubella vaccine)
- Polio vaccine
- Rotavirus vaccine
- Smallpox vaccine
- Yellow fever vaccine
- BCG vaccine (used in some countries for tuberculosis)
- Natalizumab (Tysabri®)
- Pimecrolimus (Elidel®)
- Sipuleucel-T (Provenge®)
- Tacrolimus (Prograf®)
- Tofacitinib (Xeljanz®).
Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD