Leukemia Home > Sprycel Dosage

The right dose of Sprycel for you will depend on other medications you are taking, the reason you are taking it, and various other factors. This medicine comes as a tablet that is taken once a day. If you do not adequately respond to the initial dosage, your healthcare provider may increase your amount.

An Introduction to Dosing With Sprycel

The dosage of Sprycel® (dasatinib) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • The reason you are taking the medication
  • How you respond to it
  • Other medications you are taking.
 
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

Sprycel Dosage Guidelines

The recommended initial dose of Sprycel for people in the chronic phase (the earliest stage) of chronic myeloid leukemia (CML) is 100 mg a day. Your healthcare provider may increase your amount to 140 mg a day if you do not adequately respond to the initial dose.
 
The recommended initial dose for adults in the accelerated phase or blast crisis (later stages) is 140 mg a day. Your healthcare provider may increase this to 180 mg a day if you do not adequately respond to the initial dosage.
 
The standard initial dose for people with acute lymphoblastic leukemia (ALL) is 140 mg a day. Your healthcare provider may increase this amount to 180 mg a day if you do not adequately respond to the initial dosage.
 
People who take certain other medications that alter Sprycel blood levels may need higher or lower Sprycel doses (see Sprycel Drug Interactions). Also, people who experience a serious decrease in blood cell counts or other severe side effects may need to temporarily stop taking Sprycel until the side effect improves. Sprycel may then be restarted at a lower dose.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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