Mitoxantrone works by damaging DNA, preventing it from multiplying and dividing. When used for treating multiple sclerosis, mitoxantrone also works by preventing B-cells, T-cells, and macrophages from rapidly multiplying. These cells are thought to be involved in the immune response that causes the attack on myelin in people with MS.
(Click What Is Mitoxantrone Used For? to learn more about using this drug to treat multiple sclerosis and certain types of cancer. This article also discusses in more detail how it works and whether there are off-label uses.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click