Leukemia Home > Mitoxantrone

People who have certain types of cancer or multiple sclerosis may benefit from treatment with mitoxantrone. This prescription drug is given as an injection into a vein (an intravenous, or IV, injection). Your dosage will be based on your height, weight, and various other factors. Most people who use this medicine will experience side effects, such as nausea, fever, or hair loss.

 

What Is Mitoxantrone?

Mitoxantrone (Novantrone®) is a prescription medication that belongs to a general group of drugs known as antineoplastics. It is approved to treat people with:
   
Mitoxantrone is used in combination with other medicines in the treatment of advanced prostate cancer and ANLL. When used to treat MS, it can help reduce symptoms and the number of MS relapses. Relapses are periods of time when symptoms are worse.
 
(Click What Is Mitoxantrone Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, mitoxantrone can cause side effects. And, like other cancer medicines, the side effects can be significant. While not everyone who uses the drug will experience problems, most people will experience at least one adverse reaction during treatment. 
 
If reactions do occur, in many cases, they are minor and are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common side effects seen with mitoxantrone include but are not limited to:
 
  • Low blood cell counts
  • Infection
  • Fever
  • Nausea and vomiting
  • Hair loss
  • Loss of menstrual period in women.
 
(Click Mitoxantrone Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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