Leukemia Home > Cancer and Mitoxantrone

People who have multiple sclerosis or certain types of cancer may receive mitoxantrone (Novantrone®). This prescription drug is specifically approved to treat the following conditions:
As an antineoplastic (anticancer) medication, mitoxantrone works by damaging DNA and blocking the action of certain enzymes that help to repair damaged DNA. As a result, DNA is unable to multiply and divide. This eventually causes the cells to die.
(For more details on how this medicine can help treat MS and cancer, click What Is Mitoxantrone Used For?. This full-length article takes a closer look at how this medication works, who it is approved for, and possible off-label uses.)
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Last reviewed by: Kristi Monson, PharmD;
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