Vincristine is also the active ingredient in Vincasar PFS® (vincristine). Marqibo is a form of vincristine that is contained in tiny particles of fat (liposomes). Marqibo stays in the body longer than Vincasar PFS, and reaches higher levels inside tumors (compared to certain other cells, such as nerve cells). It is thought to be more effective than Vincasar PFS and to have fewer side effects.
However, it is important to note that Vincasar PFS is available in generic form, while Marqibo is not.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Marqibo [package insert]. South San Francisco, CA: Talon Therapeutics, Inc.;2012 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed November 6, 2012.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click