Leukemia Home > Fludara Dosage

When treating B-cell chronic lymphocytic leukemia with Fludara, the recommended dosage will depend on how much you weigh, how tall you are, and how you respond to the medication, among other factors. This prescription chemotherapy drug comes in the form of an injection that is given intravenously (by IV). It is usually given for 5 days in a row, every 28 days.

An Introduction to Dosing With Fludara

The dosage of Fludara® (fludarabine phosphate) your healthcare provider recommends will vary, depending on a number of factors, such as:
  • Your height and weight
  • How you tolerate the medication
  • How you respond to the medication
  • Your kidney function.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Fludara Dosage?

Like many chemotherapy medicines, Fludara doses are normally based on body surface area, which is calculated using your height and weight. Doses based on body surface area are written as milligram per meter squared (mg per m2).
The usual recommended dosage of Fludara for the treatment of B-cell chronic lymphocytic leukemia is 25 mg per m2 once a day for 5 days in a row. This 5-day treatment course is repeated every 28 days, as long as serious side effects are not present and the medication is still working. Your healthcare provider will monitor your progress and determine how long you will need treatment.
Older adults, people with kidney disease, and those who have significant bone marrow depression may need to be treated with lower doses. Your healthcare provider may also decrease your dose, recommend you take a longer break between doses, or stop treatment altogether if you experience potentially serious Fludara side effects during treatment.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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