Leukemia Home > Clolar Uses

How Does It Work?

Clolar works to treat leukemia in a couple of different ways. The drug enters cells, where it prevents DNA from replicating. Because DNA replication is necessary for cancer cells to divide, Clolar can block the growth of the leukemia cells.

Clolar also damages the mitochondrial membrane, which is an important part of the cell that provides it with usable energy. By damaging this vital cell structure, the medication can cause leukemia cells to die.
 

Is It Safe for Adults to Use Clolar?

Clolar has not been adequately studied in adults, including older adults. It is not approved for use in individuals older than age 21. In one study, adults with blood cancers did not tolerate the usual recommended Clolar dosage for children. However, the drug may be used "off-label" (in an approved fashion) in adults.
 

Other Off-Label Clolar Uses

On occasion, your healthcare provider may recommend this medicine for treating something other than the conditions discussed in this article. This is called an "off-label" use. Possible off-label uses for Clolar include treatment of the following conditions:
 
  • Acute myelocytic leukemia
  • Myelodysplastic syndrome
  • Chronic myeloid leukemia.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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