A healthcare provider may prescribe Busulfex® (busulfan injection) for adults who have chronic myelogenous leukemia. Specifically, this chemotherapy drug is given prior to a stem cell transplant to help prepare the body. Busulfex is given by IV every six hours for four days, and will be administered by a healthcare provider in a healthcare setting.
The recommended dosage is highly individualized for each person and will depend on things like your weight, how you respond to the medicine, and other medications you are taking. Side effects are common and may include nausea, mouth sores, and infections.
(Click Busulfex for a closer look at receiving Busulfex by IV, with details on how the drug is administered, how your dosage is determined, and an explanation of how it works.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Busulfex [package insert]. Rockville, MD: Otsuka America Pharmaceutical, Inc.;2011 April.
Busulfan. Drug Facts and Comparisons. Drug Facts and Comparisons 4.0 [online]. 2012. Available from Wolters Kluwer Health, Inc. Accessed September 10, 2012.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed September 10, 2012.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed September 10. 2012.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed September 10, 2012.
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