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Leukeran Uses
A healthcare provider may prescribe Leukeran to treat chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and Hodgkin's lymphoma in adults. The medication works by disrupting how the cancer cells multiply. While Leukeran can help relive cancer symptoms, it does not cure the disease. There are also some off-label Leukeran uses, such as treating ovarian or testicular cancer.
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Leukeran® (chlorambucil) is a prescription chemotherapy medication approved to treat people with certain types of blood cancers. Specifically, it is used in the treatment of the following cancers:
- Chronic lymphocytic leukemia
- Non-Hodgkin's lymphoma
- Hodgkin's lymphoma.
Leukemia is a cancer that affects the blood and bone marrow, the middle part of certain bones that produces blood cells. Leukemia occurs when the bone marrow produces a large amount of abnormal blood cells that grow out of control. These abnormal blood cells eventually crowd out normal, healthy blood cells. This can lead to serious problems, including bleeding, anemia, and infection.
Leukemia is generally classified by how quickly the disease develops and worsens (chronic versus acute), and by the type of blood cell affected (lymphoid versus myeloid) (see Types of Leukemia). Chronic lymphocytic leukemia (also sometimes called chronic lymphatic leukemia, or CLL) is a slow-growing leukemia that starts in the lymphocytes.
Leukeran does not cure CLL but may help reduce symptoms. This is known as palliative care.
Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD



