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Leukeran and Breastfeeding
Due to unknown risks, the manufacturer of Leukeran (chlorambucil) recommends that women not breastfeed while undergoing treatment with this drug. No studies have been done to determine whether this drug passes through breast milk or if it would harm a nursing infant. However, Leukeran is associated with potentially dangerous side effects, which may pose a risk to a baby whose mother takes it while breastfeeding.
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Leukeran® (chlorambucil) is a prescription medication used to treat certain types of leukemia and lymphoma. It is unknown whether this drug passes through breast milk. Therefore, if you are breastfeeding or plan to start, you should talk to your healthcare provider prior to taking Leukeran.
No research has been done on Leukeran and breastfeeding. Therefore, it is not known whether the medication passes through breast milk, or if it would harm a nursing child. While this lack of information is frustrating, it is important to keep in mind that studies of medications are rarely done in breastfeeding women, as this would usually expose an infant, who will not directly benefit from the medication, to possible risks.
Leukeran is associated with potentially serious side effects, and the risk of these side effects in a nursing infant cannot yet be ruled out. Because of the potential risk of dangerous side effects, it is generally recommended that women not breastfeed while taking Leukeran.
You should discuss breastfeeding and Leukeran use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD