Iclusig Uses

How Does It Work?

Iclusig belongs to a group of medicines known as tyrosine kinase inhibitors. Tyrosine kinases are proteins found in the body that control cell function, including cell growth. Iclusig works by blocking the signal of certain tyrosine kinases, including but not limited to:
  • A mutated kinase known as T315I mutant ABL
  • A kinase that is resistant to treatment with other tyrosine kinase inhibitors.
By inhibiting the activity of T315I mutant ABL and other kinases, Iclusig slows down or stops the production of the abnormal blood cells.

Is It Safe for Children to Use Iclusig?

Iclusig is not approved for use in individuals younger than 18 years old, as it has not been adequately studied in this age group. Talk to your child's healthcare provider about the risks and benefits of using Iclusig in children.

Can Older Adults Use It?

Yes, older adults can use this medicine. However, some older adults may be more sensitive to Iclusig side effects and may need to be monitored more closely.

Off-Label Iclusig Uses

On occasion, your healthcare provider may recommend this medication for treating something other than the conditions discussed in this article. This is called an "off-label" use. At this time, there are no universally accepted off-label uses for Iclusig.
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