Your healthcare provider will consider other medications you are taking, other medical conditions you have, and several other factors before determining your Iclusig dosage. This chemotherapy drug comes as a tablet that is usually taken once daily. People who develop serious side effects or who are taking certain medications may need a lower amount.
The dose of Iclusig® (ponatinib) your healthcare provider recommends will vary, depending on a number of factors, including:
- How you respond to the medication
- Whether you experience side effects
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
The standard recommended dosage of Iclusig for the treatment of leukemia is 45 mg once daily. If you develop serious side effects, your healthcare provider may reduce your amount to 30 mg once daily or even 15 mg in the case of severe side effects. If potentially dangerous side effects occur, you may need to stop taking Iclusig, either temporarily or permanently.
Some other medications interact with Iclusig, increasing the level of medication in the bloodstream. If you are taking any of these drugs, a lower dosage of 30 mg once daily may be recommended (see Iclusig Drug Interactions for a list of these medications).
Some considerations to keep in mind during treatment with Iclusig include the following:
- This medication comes in the form of a tablet. It is usually taken by mouth once a day.
- Iclusig may be taken with or without food.
- Do not crush, cut, or chew Iclusig tablets. They must be swallowed whole.
- You should avoid consuming grapefruit or grapefruit juice while during treatment. This is because grapefruit products may cause too much of the medicine to be absorbed from your digestive tract into your body.
- Try to take your dose at the same time each day to keep an even level of Iclusive in your bloodstream.
- For the medication to work properly, it must be taken as prescribed. Do not stop taking it just because you feel better.
- If you are unsure about anything related to your Iclusig osage, please talk with your healthcare provider, nurse, or pharmacist.