Gleevec Drug Interactions

Gleevec Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Gleevec is combined with any of the drugs listed above.
 
Acetaminophen
Taking acetaminophen during Gleevec treatment may increase your risk for liver toxicity. It is generally recommended that people who take this drug limit their acetaminophen use to no more than 1300 mg per day. Talk to your healthcare provider about using acetaminophen during Gleevec treatment.
 
Alfuzosin
Combining Gleevec with alfuzosin can increase alfuzosin blood levels, increasing your risk for potentially serious side effects. In most cases, these drugs should not be taken together.
 
Almotriptan
Gleevec can increase the amount of almotriptan in your blood, possibly increasing your risk for side effects. Your healthcare provider may need to give you a lower almotriptan dosage, or a different medicine altogether, if you are taking Gleevec.
 
Budesonide
Gleevec can increase the level of budesonide in your body, potentially increasing your risk for budesonide side effects. This interaction is more of a concern with budesonide capsules than with the inhaled formula. Your healthcare provider may choose to give you a lower budesonide dosage if you take it with Gleevec.
 
Certain Statin Medications
Gleevec may increase the level of certain statin medications in the blood, increasing the risk for potentially serious side effects affecting the muscles. In general, people taking Gleevec should not receive lovastatin or simvastatin.
 
Colchicine
Gleevec increases blood levels of colchicine, which could increase your risk for potentially serious colchicine side effects. Do not take these medications together without first talking to your healthcare provider. You may need a lower colchicine dosage.
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Gleevec Medication Information

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