Fludara Warnings and Precautions

Discuss your medical history with your healthcare provider before starting chemotherapy treatment with Fludara. Although this can be an effective form of chemotherapy, it may not be the best option for people who have kidney disease, severe bone marrow depression, or a weakened immune system. Safety precautions with Fludara also include warnings of serious drug interactions, allergic reactions, and dangerously low blood cell counts.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to receiving Fludara® (fludarabine phosphate) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Severe bone marrow depression (extremely low counts of white blood cells, red blood cells, or platelets)
  • A condition that causes a weakened immune system
  • A history of infections because your immune system was weak
  • Received previous chemotherapy or radiation treatment
  • Plans to receive a vaccination
  • Had an autoimmune reaction in which the immune system attacks the body's blood cells, such as:
    • Hemolytic anemia
    • Autoimmune thrombocytopenia
    • Evans syndrome
    • Acquired hemophilia
  • Plans to have surgery
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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