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Cytoxan Drug Interactions
Medicines like rifamycin antibiotics and certain anticonvulsants can potentially cause drug interactions with Cytoxan. These interactions can alter the levels of some medicines in your blood -- and it may be necessary for your healthcare provider to adjust your dosages. Other medicines that may cause Cytoxan drug interactions can include anthracycline chemotherapy medications and "live" vaccinations.
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Cytoxan® (cyclophosphamide) can potentially interact with certain other medications. Some of these medicines that may lead to Cytoxan interactions include:
- Anthracycline chemotherapy medications, including:
- Daunorubicin (Cerubidine®, DaunoXome®)
- Doxorubicin (Adriamycin®, Doxil®)
- Epirubicin (Ellence®)
- Idarubicin (Idamycin®)
- Mitoxantrone (Novantrone®)
- Valrubicin (Valstar®)
- Certain anticonvulsants, including:
- "Live" vaccinations, including:
- Chickenpox vaccine (varicella vaccine)
- FluMist® (the nasal vaccine for influenza; the injected vaccine is not live)
- MMR vaccine (measles, mumps, rubella vaccine)
- Polio vaccine
- Rotavirus vaccine
- Smallpox vaccine
- Yellow fever vaccine
- BCG vaccine (used in some countries for tuberculosis)
- Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD