Chronic Myelogenous Leukemia

Complete Blood Count
A complete blood count (CBC) is a procedure in which a sample of blood is drawn and checked for the:
  • Number of red blood cells, white blood cells, and platelets
  • Amount of hemoglobin (the protein that carries oxygen) in the red blood cells
  • Portion of the sample made up of red blood cells.
Blood Chemistry Studies
Blood chemistry studies are procedures in which a blood sample is checked to measure the amounts of certain substances released into the blood by organs and tissues in the body. A higher or lower than normal amount of a substance can be a sign of disease in the organ or tissue that produces it.
Cytogenetic Analysis
A cytogenetic analysis is a test in which cells in a sample of blood or bone marrow is viewed under a microscope to look for certain changes in the chromosomes, such as the Philadelphia chromosome.
Bone Marrow Aspiration and Biopsy
A bone marrow aspiration and biopsy entails the removal of a small piece of bone and bone marrow by inserting a needle into the hipbone or breastbone. A pathologist will then view both the bone and bone marrow samples under a microscope to look for abnormal cells.

Phases of Chronic Myelogenous Leukemia

After chronic myelogenous leukemia has been diagnosed, tests are done to find out if the cancer has spread -- a process called staging. However, there is no standard staging system for CML. Instead, the disease is classified by phase. The phases of CML include:
  • Chronic phase
  • Accelerated phase
  • Blastic phase
  • Relapsed.
It is important to know the phase in order to plan treatment.
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