Childhood AML Treatment

Phases of Childhood AML Treatment

Childhood AML treatment usually has two phases: induction therapy and consolidation/intensification therapy. At times, other therapies are used as well.
Induction Therapy
Induction therapy is the first phase of childhood AML treatment. The purpose of induction therapy is to kill the leukemia cells in the blood and bone marrow, which will put the leukemia into remission.
Consolidation/Intensification Therapy
Consolidation/intensification therapy is the second phase of childhood AML treatment that begins once the leukemia is in remission. The purpose of post-remission therapy is to kill any remaining leukemia cells that may not be active but that could begin to regrow and cause a relapse.
Other Therapies
A type of childhood AML treatment called central nervous system (CNS) sanctuary therapy may be given during the induction phase of childhood AML treatment. CNS sanctuary therapy may be given, because chemotherapy that is given by mouth or injected into a vein may not reach leukemia cells in the CNS (brain and spinal cord). In the CNS, the cells are able to find "sanctuary" (hide) in the CNS. CNS sanctuary therapy and radiation therapy are able to reach leukemia cells in the CNS and are given to kill the leukemia cells and prevent the cancer from recurring (coming back). CNS sanctuary therapy is also called CNS prophylaxis.

Childhood AML Treatment Options

The four types of standard childhood AML treatment options that are used include:
  • Chemotherapy
  • Radiation therapy
  • Stem cell transplantation
  • Other drug therapies.
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