Childhood AML Treatment by Phase

Childhood AML treatment by phase is used to describe the AML subtype and identify whether the leukemia has spread outside the bone marrow. In order to plan the best treatment, childhood AML treatment by phase is used instead of AML treatment by stage. Childhood AML treatment by phase includes untreated, in remission, and recurrent.

 

Childhood AML Treatment by Phase: An Overview

The extent, or spread, of cancer is usually described in stages. However, in childhood acute myeloid leukemia (AML), the subtype of AML and whether the leukemia has spread outside the blood and bone marrow are used, instead of the stage, to plan treatment. Acute myeloid leukemia is also known as acute myelogenous leukemia.
 
For treatment purposes, childhood AML is described by phases, which include:
 
  • Untreated
  • In remission
  • Recurrent.
 
Untreated Childhood Acute Myeloid Leukemia
Treatment of untreated childhood acute myeloid leukemia (AML) will depend on the subtype of AML and may include:
 
  • Combination chemotherapy
  • Intrathecal chemotherapy with or without radiation therapy to the brain
  • All-trans retinoic acid (ATRA) with chemotherapy
  • Arsenic trioxide therapy.
 
Childhood Acute Myeloid Leukemia in Remission
Treatment of childhood acute myeloid leukemia (AML) during the remission phase will depend on the subtype of AML and may include combination chemotherapy or stem cell transplantation.
 
Recurrent Childhood Acute Myeloid Leukemia
Treatment of recurrent childhood acute myeloid leukemia (AML) will depend on the subtype of AML, and may include combination chemotherapy, with or without stem cell transplantation, or all-trans retinoic acid (ATRA) or arsenic trioxide therapy.
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Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD