Campath Uses

How Does It Work?

An antibody (also known as an immunoglobulin) is a protein made by the immune system. Antibodies attach to substances in the body called antigens, marking them for destruction by the immune system.
 
Campath is a synthetic, or manufactured, antibody. It works by binding to CD52, a specific antigen found on the surface of a variety of white blood cells, including leukemia cells.
 
By binding to the CD52 antigen on leukemia cells, Campath signals the immune system to attack leukemia cells. However, CD52 is also found on healthy cells, so Campath may signal the immune system to attack healthy cells too, which can lead to potentially serious side effects.
 

Can Children Use Campath?

Campath is not approved for use in children (usually defined as individuals younger than 18 years of age), as it has not been adequately studied in this group. Talk to your child's healthcare provider about the risks and benefits of using Campath in children.
 

Can Older Adults Use It?

There were not enough older adults in clinical trials to determine if older adults will respond differently to Campath than younger age groups. In general, older adults may be more sensitive to some of the Campath side effects, and may need to be carefully monitored.
 

Off-Label Uses for Campath

On occasion, your healthcare provider may recommend this product for something other than the condition discussed in this article. This is called an "off-label" use. Campath may be used off-label to:
 
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Campath Medication Information

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