Busulfex Uses

How Does This Medicine Work?

Busulfex is part of a group of drugs called alkylating agents. In general, alkylating agents work by causing strands of DNA to bond to each other and become linked (this is known as "cross-linking"). The linked strands cannot uncoil and separate, which is necessary for the DNA to replicate. Because DNA replication is essential for cells to grow and multiply, Busulfex may prevent cancer cells from growing and multiplying.

Is It Safe for Children to Use Busulfex?

Busulfex is not approved for use in children, as it has not been adequately studied in this age group. However, this does not mean the medicine cannot be used in children. In fact, it may be used off-label prior to a stem cell transplant in a child. Talk with your child's healthcare provider about the particular benefits and risks of giving this medicine to children.

Can Older Adults Use It?

Older adults can be treated with Busulfex. However, they may be more sensitive to the effects of the drug and may, therefore, need to be monitored more closely.

Off-Label Busulfex Uses

On occasion, your healthcare provider may recommend this medicine for something other than the uses discussed in this article. This is called an "off-label" use. Busulfex may be used off-label to prepare the body for stem cell transplant in people with other types of leukemia, lymphoma, or multiple myeloma.
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Busulfex Drug Information

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