Busulfex Side Effects

It can be difficult to predict whether you will experience problems while using Busulfex. However, as with other chemotherapy drugs, side effects are common with Busulfex, and most people who use this drug will develop some type of reaction. Some of the most common problems include nausea, vomiting, and loss of appetite. More serious reactions, such as infections and bleeding, may require medical treatment.

An Introduction to Busulfex Side Effects

As with any chemotherapy medicine, Busulfex® (busulfan injection) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some side effects can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with Busulfex. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Busulfex

Busulfex has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people given the drug were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, common Busulfex side effects included:
Other common reactions, occurring in 23 percent to 77 percent of people, included:
  • Low levels of certain electrolytes in the blood (magnesium, potassium, and calcium)
  • Anxiety
  • Abdominal (stomach) pain
  • Headache
  • High blood sugar (hyperglycemia)
  • Rash
  • Weakness and lack of strength
  • Chills
  • Pain
  • Increased heart rate (tachycardia)
  • Heartburn or indigestion
  • High levels of bilirubin (a yellowish pigment) in the blood, which could be a sign of liver damage
  • Runny or stuffy nose
  • Lung problems
  • Swelling of the arms, hands, legs, ankles, feet, or other body areas
  • Increases in certain liver enzymes
  • Dizziness
  • Cough
  • Nosebleed
  • Shortness of breath
  • Itching
  • Dry mouth
  • Pain or discomfort in the rectal area
  • Nosebleed
  • Swelling at the injection site
  • Hot flashes and flushing (sudden redness and warmth of the face, neck, and chest area)
  • Chest pain
  • Back pain
  • Abdominal enlargement (swelling or bloating in the stomach area)
  • Depression.
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Busulfex Drug Information

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