Busulfex Overdose

If you receive too much Busulfex (busulfan injection), it may cause infections, seizures, and even death. The specific effects will depend on how much of the drug was given and whether it was combined with other products. Seek medical treatment right away if you believe you have received an overdose. A healthcare provider may administer certain medications or provide supportive care.

Can You Receive Too Much Busulfex?

Busulfex® (busulfan injection) is a prescription medication that belongs to a group of drugs known as alkylating agents. Because Busulfex is given in a healthcare setting by a trained healthcare provider, an intentional overdose is unlikely to occur.
However, as with most medications, there is a possibility that an accidental overdose could happen. The specific effects of an overdose would vary, depending on a number of factors, such as the Busulfex dosage and whether it was given with any other medications or substances.

Symptoms of an Overdose

Based on reports of overdoses with busulfan (the active ingredient in Busulfex), the known effects of the medication, and animal studies, possible symptoms of an overdose may include but are not limited to:
  • Reduced white blood cells in the body, which could cause infections
  • Reduced red blood cells (anemia)
  • Reduced platelets, which could cause dangerous bleeding
  • Nausea and vomiting
  • Mouth sores
  • Diarrhea
  • Cataracts
  • Seizures
  • Death.

Treatment for a Busulfex Overdose

Treatment will usually include supportive care, which consists of treating the symptoms that occur as a result of the overdose. Supportive treatment may include close monitoring of blood cell counts and administering antibiotics to treat or prevent infections. Dialysis may also be used to help remove Busulfex from the body.
It is important that you seek prompt medical attention if you believe you may have overdosed on this medication.
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Busulfex Drug Information

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