Busulfex Drug Interactions

Mifepristone
Mifepristone may increase the level of Busulfex in your body, which could increase your risk for side effects. This interaction is more likely to be a concern when mifepristone is taken on an ongoing basis, as opposed to one-time mifepristone doses that are used to end an early pregnancy.
 
Phenytoin
Phenytoin may decrease blood levels of Busulfex. However, phenytoin is often given to help prevent seizures during Busulfex treatment. Therefore, your dose will likely already be adjusted based on this interaction.
 
Roflumilast
Combining roflumilast with Busulfex may further increase your risk for developing infections. Talk to your healthcare provider about this potential interaction before using these drugs together.
 
Sipuleucel-T
Busulfex may decrease the effectiveness of sipuleucel-T. This is because sipuleucel-T is thought to work by stimulating the body's immune system, while Busulfex decreases the activity of the immune system. Talk to your healthcare provider about this possible interaction before using these drugs together.
 
Warfarin
Chemotherapy medicines, including Busulfex, have been reported to both increase and decrease the effects of warfarin. If you take warfarin during Busulfex treatment, your healthcare provider may need to closely monitor your prothrombin time ("protime" or PT) and international normalized ratio (INR) to make sure you are receiving the right amount of warfarin.
 

Final Thoughts

It is possible that not all Busulfex drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
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Busulfex Drug Information

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