Busulfex Drug Interactions

Busulfex Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Busulfex is combined with any of the drugs listed above.
 
Acetaminophen
Acetaminophen may increase blood levels of Busulfex, potentially increasing the risk for side effects. Let your healthcare provider know if you take any product containing acetaminophen during Busulfex treatment, or in the three days before you begin to receive your doses.
 
Amphotericin B
Combining certain chemotherapy medicines, including Busulfex, with amphotericin B could increase the risk for potentially serious amphotericin B side effects, such as low blood pressure (hypotension) and lung problems. Your healthcare provider may choose to closely monitor you for side effects if you use these medicines together.
 
Biologic and Immunologic Medications
Taking certain biologic and immunologic medicines during Busulfex treatment could increase the risk for potentially serious side effects, including infections, anemia, and possibly the development of other cancers. Busulfex should not be used in combination with some biologic or immunologic medicines, while other combinations will require careful monitoring. Talk to your healthcare provider about this potential interaction if you are taking biologic or immunologic medicines.
 
Clozapine
Using clozapine and Busulfex together may cause dangerously low white blood cell counts and increase your risk for potentially life-threatening infections. Talk to your healthcare provider about this potential interaction if you take clozapine. Do not stop taking clozapine, however, unless your healthcare provider specifically tells you to do so.
 
CYP 3A4 Inducer Medications
The liver breaks down Busulfex using enzymes known as CYP 3A4 enzymes, and medications known as CYP 3A4 inducers can increase the activity of these enzymes. Thus, combining Busulfex with one of these drugs may decrease the level of Busulfex in your body, possibly making it less effective. Your healthcare provider may need to monitor you more closely if you combine these medicines.
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Busulfex Drug Information

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