Busulfex Dosage

Administered by a healthcare provider, Busulfex comes as an injection that is given into a vein. It is usually given every six hours for four days. The specific Busulfex dosage your healthcare provider prescribes will be based on how much you weigh, how you respond to the drug, and a number of other factors.

An Introduction to Dosing With Busulfex

The dose of Busulfex® (busulfan injection) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your weight
  • How you respond to and tolerate the medication
  • Other medical conditions you may have
  • Other medications you are taking.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Busulfex Dosage?

The usual recommended dose of Busulfex prior to a stem cell transplant is 0.8 mg per kg body weight (about 0.36 mg per lb), given every six hours for four days (a total of 16 doses). People who are obese may receive amounts based on what is known as their adjusted ideal body weight, as opposed to their actual weight. In some cases, doses may be adjusted based on Busulfex blood levels.
Busulfex is normally used as part of a treatment regimen that includes cyclophosphamide (Cytoxan®). The first dose of cyclophosphamide is usually given six or more hours after the last dose of Busulfex three days before the stem cell transplant.

General Information on Using Busulfex

Some considerations to keep in mind during treatment with Busulfex include the following:
  • This medicine comes as a liquid that is given as an injection into a vein (an intravenous, or IV, injection). It is usually given four times a day for four days.
  • The injection is given by a trained healthcare provider in a healthcare setting, such as a hospital or clinic.
  • It will take about two hours to receive your Busulfex injection.
  • Your healthcare provider will give you other medicines, such as anti-nausea and anti-seizure medicines, to help prevent side effects.
  • Busulfex can be irritating to the skin. Tell your healthcare provider immediately if you have pain, redness, or swelling at the IV site (the site where the needle goes into your vein).
  • For this drug to work properly, it must be used as prescribed.
  • If you are unsure about anything related to your Busulfex dosage, please talk with your healthcare provider or pharmacist.
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Busulfex Drug Information

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