Busulfex and Breastfeeding

It is unclear if Busulfex (busulfan injection) passes through breast milk. However, women are generally advised to not breastfeed during treatment, as this drug is associated with potentially serious risks like low blood cell counts and the risk of developing other types of cancer. Before using Busulfex while breastfeeding, discuss the potential risks with your healthcare provider.

Can Breastfeeding Women Receive Busulfex?

Busulfex® (busulfan injection) is a prescription medication used before stem cell transplants in people with chronic myelogenous leukemia. At this time, it is unknown whether Busulfex passes through breast milk. The manufacturer recommends that women not breastfeed while undergoing treatment with this drug.

More Information on Busulfex and Breastfeeding

Busulfex has not been adequately studied in breastfeeding women. Therefore, it is not known whether the medicine passes through breast milk, or if it would harm a nursing child.
There is one report describing the use of Busulfex in a woman who was breastfeeding. In this report, no significant problems occurred in the nursing child. However, one report is not nearly enough information to determine whether the drug is safe for use in breastfeeding women.
In fact, because of the serious side effects associated with its use, such as low blood cell counts and the possible risk for developing other types of cancer, many experts recommend that women stop breastfeeding during treatment with Busulfex.
Busulfex is only given for four days. If you are thinking about breastfeeding, talk to your healthcare provider about how long you should wait after receiving this medicine before breastfeeding your child.

Talking With Your Healthcare Provider

You should discuss breastfeeding and Busulfex use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
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Busulfex Drug Information

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