Busulfan is a medication used for slowing down the growth of a certain type of cancer known as chronic myelogenous leukemia. The tablets are taken once daily and work by interfering with the way DNA replicates. Side effects may include low blood cell counts, which may lead to infections, bleeding, and anemia.

What Is Busulfan?

Busulfan (Myleran®) is a prescription medication approved to treat chronic myelogenous leukemia, a type of cancer of the blood cells. Chronic myelogenous leukemia is also called chronic myeloid leukemia or chronic granulocytic leukemia. Busulfan belongs to a group of chemotherapy medicines known as alkylating agents.
(Click What Is Busulfan Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any chemotherapy medicine, busulfan can cause side effects, some of which can be significant and potentially serious. In fact, most people will experience some type of side effect during treatment. Talk with your healthcare provider about ways to prevent or lessen reactions to this drug.
Common side effects of busulfan include but are not limited to:
  • Decreased levels of white blood cells, which could increase the risk for infections
  • Decreased levels of red blood cells, which could cause anemia
  • Decreased levels of platelets, which could increase the risk for bleeding.

(Click Busulfan Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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