Busulfan

Important Information for Your Healthcare Provider

Talk with your healthcare provider prior to taking this medication if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Lung disease
  • A seizure disorder
  • A history of head trauma
  • Had radiation treatment or previous chemotherapy
  • Any allergies, including to foods, dyes, or preservatives.

Also, let your healthcare provider know if you are:
 

 
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

 
(Click Precautions and Warnings With Busulfan to learn more, including information on who should not take the drug.)
 

How Does It Work?

Busulfan is part of a group of medications called alkylating agents. In general, alkylating agents work by causing strands of DNA to bond to each other and become linked (this is known as "cross-linking"). The linked strands cannot uncoil and separate, which is necessary for the DNA to replicate. Because DNA replication is essential for cells to grow and multiply, alkylating agents like busulfan prevent cell growth and multiplication, and may cause cell death.
 
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Busulfan Chemotherapy Information

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