An Introduction to Dosing With Arzerra
There is only one standard dosage of
Arzerra® (
ofatumumab), regardless of your age or weight. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
The usual recommended initial dosage of Arzerra for the treatment of
chronic lymphocytic leukemia (
CLL) is 300 mg. After the initial dosage, the amount will be increased to 2000 mg once a week for seven more doses, and then once every four weeks for four doses. Treatment is finished after 12 doses, which normally takes 24 weeks.
Because of the risk for infusion reactions (serious reactions to the medication that may occur during or shortly after receiving the dose) from the Arzerra injection, the medication will be given slowly over several hours. The infusion may need to be interrupted if reactions occur.
In addition, your healthcare provider will give you other medicines 30 minutes to 2 hours before each Arzerra dosage to help prevent infusion reactions. This is known as premedication. Premedication with this particular treatment usually includes the following:
General Information on Receiving Arzerra
Some considerations to keep in mind during treatment with Arzerra include the following:
- This medication comes in the form of a liquid solution that is given as an intravenous (IV) infusion (a slow injection into a vein) every one to four weeks.
- The injection will be given by a healthcare provider in a healthcare setting, such as a doctor's office or clinic. It can take several hours to receive your dose of Arzerra.
- You will be given other medications by mouth or intravenously (by IV) 30 minutes to 2 hours before your Arzerra dosage, to help reduce the chance that you will have a reaction to the infusion.
- For the medication to work properly, it must be used as prescribed. Make sure to keep all of your appointments to receive Arzerra.
- If you are unsure about anything related to your dosage or Arzerra dosing in general, please talk to your healthcare provider or pharmacist.
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