AML

Stages of AML

Once AML has been diagnosed, tests are done to find out if the cancer has spread to other parts of the body. The extent, or spread, of cancer is usually described as stages. However, in AML, there is no standard staging system. Instead, the disease is described as untreated, in remission, or recurrent. In AML, the subtype and whether the leukemia has spread outside the blood and bone marrow are used to plan treatment.
 

Treatment of AML

Different types of treatment are available for AML. Some treatments are standard (the currently used treatment), and some treatments are being tested in clinical trials.
 
Current childhood AML treatment options include:
 
  • Chemotherapy
  • Radiation therapy
  • Chemotherapy with stem cell transplant.
 
There are also two phases of treatment used for childhood AML: induction therapy and consolidation/intensification therapy.
 
Current treatment options in adults include:
 
  • Chemotherapy
  • Radiation therapy
  • Stem cell transplantation
  • Other drug therapies.
 
There are also two phases of treatment for adult AML: remission induction therapy and maintenance therapy.
 
Choosing the most appropriate treatment for AML is a decision that ideally involves the affected person, the family, and the healthcare team.
 

The Prognosis for AML

The prognosis and treatment options for AML will depend on:
 
  • The person's age, general health, and number of white blood cells present at diagnosis
  • Whether the AML was caused by previous anticancer treatment
  • The subtype
  • How well the leukemia responds to initial treatment
  • Whether the AML is untreated or has recurred (come back) after being treated
  • Whether there is a history of a blood disorder, such as myelodysplastic syndrome
  • Whether the AML has spread to the central nervous system (brain and spinal cord) or to other parts of the body.
 
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AML Leukemia

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