Childhood ALL Treatment

Chemotherapy With Stem Cell Transplant for Childhood ALL Treatment
Stem cell transplant is a method of giving chemotherapy and replacing blood-forming cells destroyed by the cancer treatment. In stem cell transplant, stem cells (immature blood cells) are removed from the blood or bone marrow of a donor and are frozen for storage. After the chemotherapy is completed, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the body's blood cells.

Clinical Trials for New Childhood ALL Treatment

Many children with ALL participate in clinical trials. These studies test a new drug or a new combination of drugs, often comparing them to the current standard treatment. A participant will usually be assigned to the standard group or the new group by chance in a process called randomization. It is not known at the start of the trial whether the new treatment is better than, the same as, or worse than the standard treatment.
Clinical trials for children with ALL often enroll large numbers of children and are conducted at children's cancer centers nationwide. Much of the success in curing children with ALL is the result of better treatments that were identified in clinical trials. Currently, doctors are conducting clinical trials to improve ALL treatments and to reduce side effects.
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